Dr. Paola Valentino | Biomarkers | Best Researcher Award

🔬 Dr. Paola Valentino, a trailblazing leader in biomarkers at the University of Turin, spearheads groundbreaking initiatives in translational research. 🌐 As the driving force behind the establishment of the Department’s biobank, she expertly manages cryogenic facilities, informed consent procedures, and sample/data documentation. Her extensive research fellowship at the Neuroscience Institute focused on Multiple Sclerosis and NMOSD, delving into biomarkers like Neurofilament Light Chain and anti-aquaporin 4 antibodies. 🧪 Dr. Valentino excels in quality management, shaping the CRESM Biobank’s protocols and legal documents while actively contributing to national and international biobanking initiatives. 🌍 Her rich background, spanning from gene expression analysis to board certification in clinical and analytical biochemistry, showcases her multidisciplinary prowess. 🎓 Fluent in Italian, with proficiency in English and French, Dr. Valentino is a dynamic force in the intersection of science, ethics, and biobanking standards. 🌟

Profile:

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Education:

👩‍🎓 Dr. Paola Valentino, a Turin native, embarked on her academic journey with a Bachelor’s degree in Medical Biotechnology (L1) from the University of Turin in 2003. 🎓 Her commitment to excellence continued as she earned a Master’s degree in Medical Biotechnology (9/S) on 23/07/2003, solidifying her expertise in the field. 🧪 Driven by a passion for analytical biochemistry, she achieved Board Certification in Clinical and Analytical Biochemistry from the University of Turin on 27/07/2005. 🏆 These educational milestones laid the foundation for her remarkable career as a leader in biomarker research and biobanking. 🌟

Experience:

🌟 Dr. Paola Valentino is a dynamic force in the world of biomarkers, currently serving as Technical Administrative Personnel at the University of Turin since 03/07/2023. 🏛️ Her impactful role involves establishing the biobank for the Department of Clinical and Biological Sciences, overseeing cryogenic facilities, documentation, informed consent, and managing samples and data. 🧪 Concurrently, she engages in cutting-edge translational research activities, focusing on biomarkers.

🔬 Prior to her current position, Dr. Valentino held a significant role at the Neuroscience Institute Cavalieri Ottolenghi (NICO)/University Hospital San Luigi Gonzaga from 18/09/2006 to 30/06/2023. During this tenure, her research spanned multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD). Notably, she pioneered studies on Neurofilament Light Chain as a biomarker, validated methods for anti-aquaporin 4 antibodies, and explored the diagnostic potential of anti-potassium channel KIR4.1 antibodies.

🌐 Dr. Valentino’s impact extends to quality management in the CRESM biobank since 08/04/2021, where she defines sample collection protocols, updates databases, implements biobank software, and ensures compliance with ethical and legal standards, including GDPR. 🌍 Her diverse expertise also includes participating in international biobanking working groups, contributing to standards like UNI ISO 20387, and collaborating on gene expression analysis with the Italian Foundation for Multiple Sclerosis. 🤝 Dr. Valentino’s multifaceted contributions solidify her as a key figure in the intersection of research, biobanking, and quality management.

Publication:

• Serum Biomarker Profiles Discriminate AQP4 Seropositive and Double Seronegative Neuromyelitis Optica Spectrum Disorder
  • Author: Carta, S., Dinoto, A., Capobianco, M., … Marignier, R., Mariotto, S.
  • Year: 2024
  • Journal: Neurology(R) Neuroimmunology & Neuroinflammation, 11(1), pp. e200188
• Ocrelizumab Extended Interval Dosing in Primary Progressive Multiple Sclerosis: An Italian Experience
  • Authors: Zanghì, A., Ferraro, D., Callari, G., … Avolio, C., D’amico, E.
  • Year: 2024
  • Journal: Current Neuropharmacology, 22(2), pp. 339–345

• Cerebrospinal fluid neurofilament light chains predict early disease activity in Multiple Sclerosis
  • Authors: Toscano, S., Oteri, V., Chisari, C.G., … Zappia, M., Patti, F.
  • Year: 2023
  • Journal: Multiple Sclerosis and Related Disorders, 80, 105131

• Correction to: Daytime sleepiness and sleep quality in Charcot–Marie–Tooth disease (Journal of Neurology)
  • Authors: Bellofatto, M., Gentile, L., Bertini, A., … Iabichella, G., Barone, S.
  • Year: 2023
  • Journal: Journal of Neurology, 270(11), pp. 5569–5570

• Daytime sleepiness and sleep quality in Charcot–Marie–Tooth disease
  • Authors: Bellofatto, M., Gentile, L., Bertini, A., … Iabichella, G., Barone, S.
  • Year: 2023
  • Journal: Journal of Neurology, 270(11), pp. 5561–5568

• Data monitoring roadmap. The experience of the Italian Multiple Sclerosis and Related Disorders Register
  • Authors: Mosconi, P., Guerra, T., Paletta, P., … Zaffaroni, M., Zarbo, R.
  • Year: 2023
  • Journal: Neurological Sciences, 44(11), pp. 4001–4011

• Serum Neurofilaments are a reliable biomarker to early detect PML in Multiple Sclerosis patients
  • Authors: Valentino, P., Malucchi, S., Bava, C.I., … Di Sapio, A., Bertolotto, A.
  • Year: 2023
  • Journal: Multiple Sclerosis and Related Disorders, 77, 104893

• Quality of care provided by Multiple Sclerosis Centers during Covid-19 pandemic: Results of an Italian multicenter patient-centered survey
  • Authors: Altieri, M., Capuano, R., Bisecco, A., … Tedeschi, G., Gallo, A.
  • Year: 2023
  • Journal: Multiple Sclerosis and Related Disorders, 77, 104870

• The one-and-a-half syndrome: a distinctive clinical finding in a patient with multiple sclerosis
  • Authors: Fratto, E., Barone, S., Tinelli, E., … Gambardella, A., Valentino, P.
  • Year: 2023
  • Journal: Neurological Sciences, 44(9), pp. 3331–3333

• Clinical spectrum and frequency of Charcot–Marie–Tooth disease in Italy: Data from the National CMT Registry
  • Authors: Pisciotta, C., Bertini, A., Tramacere, I., … Vita, G., Pareyson, D.
  • Year: 2023
  • Journal: European Journal of Neurology, 30(8), pp. 2461–2470