Introduction of Inflammatory Neurologic Diseases
Inflammatory neurologic diseases represent a diverse group of conditions characterized by abnormal immune responses targeting the nervous system. Research in this field is essential to decipher the intricate mechanisms, improve diagnostic accuracy, and develop targeted therapeutic strategies to mitigate the impact of these diseases on patients’ lives.
Multiple Sclerosis (MS) Pathogenesis:
Investigating the immune-mediated processes that lead to demyelination in MS, ,including the role of autoreactive T cells, B cells, and genetic predisposition.
Neuromyelitis Optica Spectrum Disorder (NMOSD):
Studying the unique immune responses underlying NMOSD, particularly the role of aquaporin-4 antibodies, and developing targeted treatments.
Exploring the pathophysiology of autoimmune encephalitis, including antibody- mediated mechanisms, and optimizing immunotherapies for rapid diagnosis and treatment.
Guillain-Barré Syndrome (GBS):
Researching the immune responses in GBS, with a focus on molecular mimicry, and improving treatment strategies for this acute demyelinating disorder.
Investigating chronic inflammatory neuropathies like chronic inflammatory demyelinating polyneuropathy (CIDP) and developing personalized treatment approaches.
Advancing immunomodulatory and immunosuppressive therapies for inflammatory neurologic diseases, aiming to balance effective disease control with minimized side effects.
Neuroinflammation and Brain Health:
Examining the role of neuroinflammation in various neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, and its potential as a therapeutic target.
Biomarkers for Diagnosis:
Identifying reliable biomarkers in blood, cerebrospinal fluid, or imaging to aid in early diagnosis, monitor disease progression, and evaluate treatment response.
Pediatric Inflammatory Neurologic Diseases:
Investigating the unique challenges and treatment strategies for children and adolescents with inflammatory neurologic conditions.
Researching innovative approaches such as stem cell therapies, gene editing, and precision medicine to transform the treatment landscape for inflammatory neurologic diseases.