Subhendu Ghosh | Synaptic Plasticity | Best Researcher Award

Prof. Subhendu Ghosh: Synaptic Plasticity

Prof.Ā  Subhendu Ghosh šŸ§ šŸ”¬, a distinguished biophysicist, earned his Ph.D. and M.Phil. in Biophysics from Jawaharlal Nehru University, delving into Ligand-DNA interactions. With a profound research career, he explores Cognitive Neuroscience, unraveling the neural mechanisms of learning and emotions. His expertise extends to Ion Channels and Electrophysiology, investigating VDAC and Gap Junctions. In the realm of Apoptosis and Neuronal Disorders, he deciphers cell death mechanisms linked to conditions like Alzheimer’s. As a Theoretical Biologist, he pioneers Mathematical Models using Stochastic and Nonlinear Dynamics, employing computational analyses. Prof. Ghosh’s impactful tenure includes professorial roles and heading the Biophysics Department at the University of Delhi South Campus.

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šŸŽ“Ā Education:

Professor Subhendu Ghosh is a trailblazing biophysicist šŸ§¬ with a rich academic journey. He earned his Ph.D. in Biophysics, specializing in Ligand-DNA interactions, from Jawaharlal Nehru University in 1984. Prior to that, he obtained an M.Phil. in Biophysics in 1980 and an M.Sc. in Physics in 1978, both from Jawaharlal Nehru University. His academic journey commenced with a B.Sc. from Calcutta University (Presidency College) in 1975. Prof. Ghosh’s educational background reflects his commitment to unraveling the intricacies of biophysical phenomena, establishing him as a notable figure in the field. šŸ‘Øā€šŸ”¬āœØ

šŸ„Ā Experience:

šŸ‘Øā€šŸ”¬ Professor Subhendu Ghosh, a seasoned biophysicist, boasts a diverse research portfolio. His expertise encompasses the intricate interactions of DNA with various entities, including carcinogens, anticancer agents, and proteins, focusing on structural nuances. Proficient in spectroscopic methods like absorption, fluorescence, CD & ORD, and well-versed in NMR, he unravels the mysteries of molecular structures. Additionally, his work extends to membrane channels, such as porins and Voltage Dependent Anion Channels, employing biochemical, electrophysiological (patch-clamp), and spectroscopic techniques.

A stalwart in mathematical modeling, he navigates stochastic and nonlinear realms, exploring Fractal Geometry’s applications in biology and computers. His illustrious career spans appointments as a Professor and Head at the University of Delhi South Campus, a Guest Scientist at the Max Planck Institute in Germany, and various roles at esteemed institutions. šŸŒ With a relentless passion for unraveling biological complexities, Prof. Ghosh leaves an indelible mark on the world of biophysics.

šŸ”¬Research Interest:

šŸ§  Professor Subhendu Ghosh, a trailblazer in biophysics, delves into the realms of cognitive neuroscience, unraveling the mysteries of human learning and memory. Focused on the neural mechanisms and synaptic dynamics underlying learning, his interdisciplinary approach incorporates Behavioral Science, Neurophysiology, Computer Science (Artificial Neural Network), and Mathematics to decipher the biology of emotions.

āš” In the realm of ion channels and electrophysiology, Prof. Ghosh pioneers advanced techniques like Patch-Clamp and Bilayer Electrophysiology. His investigations on Voltage Dependent Anion Channels (VDAC) and Gap Junctions in Rat Brain Cells shed light on ion flux control, channel gating, and self-organization, especially post-phosphorylation and ligand interactions.

šŸ’” Delving into apoptosis and neuronal disorders, he explores the intricacies of cell death mediated by Cytochrome C, offering insights into conditions like Alzheimer’s, Parkinson’s, Amnesia, and Dementia through bilayer electrophysiology and patch-clamp studies.

šŸ” In theoretical biology, Prof. Ghosh’s expertise shines as he develops mathematical models using Stochastic and Nonlinear Dynamics, employing Fourier Analyses, Fractal Analysis, Noise Analysis, and Computational Analyses to unravel the complexities of biological phenomena. šŸŒšŸ”¬

šŸ”¬Publications:
  • Natalizumab for active Crohn’s disease
    • Authors: S Ghosh, E Goldin, FH Gordon, HA Malchow, J Rask-Madsen, …
    • Journal: New England Journal of Medicine
    • Year: 2003
    • Citations: 978
  • Influence of intracerebral hemorrhage location on incidence, characteristics, and outcome: population-based study
    • Authors: N Samarasekera, A Fonville, C Lerpiniere, AJ Farrall, JM Wardlaw, …
    • Journal: Stroke
    • Year: 2015
    • Citations: 143
  • Bax increases the pore size of rat brain mitochondrial voltage-dependent anion channel in the presence of tBid
    • Authors: J Banerjee, S Ghosh
    • Journal: Biochemical and biophysical research communications
    • Year: 2004
    • Citations: 97
  • Mitochondrial VDAC can be phosphorylated by cyclic AMP-dependent protein kinase
    • Authors: AK Bera, S Ghosh, S Das
    • Journal: Biochemical and biophysical research communications
    • Year: 1995
    • Citations: 94
  • Dual mode of gating of voltage-dependent anion channel as revealed by phosphorylation
    • Authors: AK Bera, S Ghosh
    • Journal: Journal of Structural Biology
    • Year: 2001
    • Citations: 62
  • Wetland macrophytes as toxic metal accumulators
    • Author: S Ghosh
    • Journal: International Journal of Environmental Sciences
    • Year: 2010
    • Citations: 58
  • Representation and computational structure-property relations of random media.
    • Authors: D McDowell, S Ghosh, S Kalidindi
    • Journal: JOM: The Journal of The Minerals, Metals & Materials Society (TMS)
    • Year: 2011
    • Citations: 57
  • Goiter prevalence and iodine nutritional status of school children in a sub-Himalayan Tarai region of eastern Uttar Pradesh
    • Authors: AK Chandra, A Bhattacharjee, T Malik, S Ghosh
    • Journal: Indian Pediatrics
    • Year: 2008
    • Citations: 56
  • The effect of amantadine on an ion channel protein from Chikungunya virus
    • Authors: D Dey, SI Siddiqui, P Mamidi, S Ghosh, CS Kumar, S Chattopadhyay, …
    • Journal: PLoS neglected tropical diseases
    • Year: 2019
    • Citations: 49
  • Phosphorylation of rat brain mitochondrial voltageā€dependent anion as a potential tool to control leakage of cytochromeā€ƒc
    • Authors: J Banerjee, S Ghosh
    • Journal: Journal of neurochemistry
    • Year: 2006
    • Citations: 44

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Assist Prof Dr Houssein Darwish | Hydrocephalus

Assist Prof Dr Houssein Darwish Leading in Hydrocephalus

Congratulations,Assist Prof Dr Houssein Darwish, on winning the esteemed Best Researcher AwardĀ from Pencis!

Dr. Houssein Darwish is a Clinical Instructor of Neurological Surgery at the American University of Beirut Medical Center. As an Attending Neurosurgery Physician from 2015 to 2017, he performed over 200 cases across diverse neurosurgical domains. Dr. Darwish served as an Instructor at Phonecia University’s Public Health Department. His extensive education includes a fellowship at the University of Virginia Medical Center and residency at the American University of Beirut Medical Center. Dr. Darwish received his Doctor of Medicine with honors and a B.S. in Biology with honors from the American University of Beirut.

JOBS

Current – Dr. Houssein Darwish currently serves as a Clinical Instructor of Neurological Surgery at the American University of Beirut Medical Center, contributing expertise to medical education and patient care.

Dr. Houssein Darwish’s impactful career in neurosurgery is marked by his role as an Attending Neurosurgery Physician from 2015 to 2017. During this period, he significantly contributed to Bikhiazi Medical Group’s Fouad Khoury Hospital, Bahman Hospital, and Rafic Harriri University Hospital. His commitment to excellence is underscored by his successful completion of over 200 cases in diverse neurosurgical domains.

Dr. Houssein Darwish’s multifaceted contributions to both clinical practice and education underscore his dedication to advancing the field of neurosurgery, making a lasting impact on patient care and the training of healthcare professionals.

Education

Dr. Houssein Darwish’s educational journey is a testament to his commitment to neurosurgery excellence. From 2017 to 2017, he underwent specialized training in Deep Brain Stimulation, Open skull base surgery, and Stereotactic surgery at Cleveland Clinic Florida, guided by Dr. Bahih Adada, Chairman of the Neuroscience Institute. šŸ§  In 2014-2015, he furthered his expertise as a Fellow at the University of Virginia Medical Center, delving into Endoscopic Neuroendocrine, nasal, and paranasal skull base, and pituitary surgery under Dr. John Jane Jr. šŸ„ Prior, he dedicated years to neurosurgical residency at the American University of Beirut Medical Center, culminating in a distinguished Doctor of Medicine in 2007 and a B.S. in Biology in 2003. šŸŒŸ

Awards

Dr. Houssein Darwish’s journey in medicine is a constellation of remarkable achievements, each award reflecting his unwavering commitment and excellence. In 2014, he proudly spoke on behalf of all medical specialties at the American University of Beirut’s annual graduationā€”a true testament to his outstanding impact.

Elevating his influence, Dr. Darwish assumed the role of Vice President of the Alpha Omega Alpha Lebanon and Middle East Chapter in 2013, demonstrating exemplary leadership within the medical community. The apex of his accolades came in 2012 with the groundbreaking Salim Hoss Award for Medical Professionalism and Humanismā€”the first of its kind awarded to a resident in the Middle East, truly setting him apart.

Dr. Darwish’s academic brilliance continued in 2006 with the award of M.D. with distinction, and earlier, in 2003, he received his B.S. with distinction. Congratulations abound for Dr. Darwish, šŸŽ‰ as these accolades not only acknowledge his individual brilliance but also serve as an inspiration to the entire medical community. šŸŒŸ

Medical CONFERENCES, MEETINGS & WORKSHOPS

In July 2017, at the World Association of Lebanese Neurosurgeons, Dr. Houssein Darwish captivated audiences as a Speaker, enlightening them on the intricacies of Endoscopic Endonasal Resection of Skull Base Tumors. His impactful contributions continued in June 2014 at the Lebanese Society of Neurological Surgery annual meeting, where he shared insights on EC-IC surgery for Moya-Moya disease.

May 2014 witnessed his engaging presentation at the Lebanese League Against Epilepsy, discussing the Resection of Motor Cortex Cortical Dysplasia. Dr. Darwish’s commitment to advancing medical knowledge extended into February 2014 at the Lebanese League Against Epilepsy, where he delved into the nuances of Functional Hemispheretomy with Motor Sparing Technique.

At the 3rd Kuwaiti-Lebanese Epilepsy meeting in February 2014, Dr. Darwish continued to showcase his expertise. In July 2013, he addressed the World Association of Lebanese Neurosurgeons, focusing on the Endoscopic Endonasal Approach for Pituitary Tumors.

In July 2010, at the Lebanese Science Meeting, Dr. Darwish shared insights into Vagal Nerve Stimulation indications and techniques. His continuous contributions spanned from May 2003 to 2014 at the Middle East Medical Assembly, leaving an enduring impact on the medical community. šŸ—“ļøšŸ‘Øā€āš•ļøāœØ

Research and Book Chapters

Dr. Houssein Darwish’s impactful contributions to research and book chapters underscore his commitment to advancing neurosurgical knowledge. In 2006, his technical lab support was acknowledged in an article published in Fisheries Research. Mastering the technique of coronary arteries perfusion on rats marked his proficiency in 2003-2004.

A pivotal moment came in 2009 when Dr. Darwish contributed to research on deep brain stimulation as a treatment for early-onset pantothenate kinase-associated neurodegeneration, published in the European Journal of Paediatric Neurology.

His collaboration with Dr. Bustany’s lab focused on Neuronal Ceroid Lipofuscinosis (NCL). Noteworthy chapters include “Craniosynostosis Surgical Management” in Neurosurgery Tricks in the Trade (2011) and “Peripheral Nerve Injury: Physical Exam and Diagnosis” (2012). In 2013, he wrote five chapters on operative dictation for various endovascular interventions.

From 2015 to 2017, Dr. Darwish co-authored research articles on topics ranging from intracranial hydatid cysts to lumbar subdural cerebrospinal fluid collection after Chiari malformation Type I decompression. Ongoing projects include the study of the modified far-lateral transatlas approach, trigeminal neuralgia caused by petrous bone endostosis, and the surgical management of CSF leaks.

In 2018, he contributed to the literature on the management of pituitary adenomas through Mononostril Endoscopic Transsphenoidal Surgery. Ongoing research involves the surgical resection of motor cortical dysplasia and a study on the frontal sinus’s anatomical relation to the supra-orbital notch in a Middle Eastern population. Dr. Darwish’s dedication to cutting-edge neurosurgical research is evident, shaping the landscape of his field. šŸ§ šŸ“ššŸ”

Languages

Dr. Houssein Darwish excels in both English and Arabic, demonstrating fluency in speaking, writing, and reading. This linguistic versatility enhances his ability to communicate effectively in diverse settings, ensuring seamless interactions whether engaged in medical discussions, research endeavors, or patient care. šŸ—£ļøšŸ“šŸŒ

Certificates

Dr. Houssein Darwish has secured vital certifications in the medical field, including Basic Life Support (BLS) obtained on June 10, 2014, and Advanced Cardiovascular Life Support (ACLS) earned on June 20, 2014. These certifications reflect his commitment to ensuring the highest standards of emergency care and life-saving interventions. šŸ©¹šŸ„

Research Foucs

The research focus of Dr. Houssein Darwish spans various domains within neurosurgery, encompassing areas such as deep brain stimulation, craniosynostosis surgical management, peripheral nerve injury, and operative dictation in endovascular interventions. His ongoing projects delve into topics like intracranial hydatid cysts, lumbar subdural cerebrospinal fluid collection post-Chiari malformation decompression, and the frontal sinus’s anatomical relation to the supra-orbital notch in a Middle Eastern population. In one word, Dr. Darwish’s research can be categorized asNeurosurgery.” šŸ§ šŸ”¬šŸ“Š

Publications Top Note

Neurosurgical Experience of Beirut Blast in the Era of Coronavirus Disease 2019 (COVID-19) from a Tertiary Referral Center- 2022

Role of the Neurointerventionalist in the Cardiac Catheterization Laboratory- 2022

Membranous obstruction of the foramen of magendie: A case report, literature review and recommendations- 2022

Spinal intradural extramedullary granular cell tumor- 2022

Glioblastoma multiforme metastasizing to the skin, a case report and literature review- 2022

Coexisting schwannoma and meningioma simulating a single cerebellopontine angle lesion: Case report and review of the literature- 2021

Frontal Sinus Morphometry in Relation to Surgically Relevant Landmarks in the Middle East Population: Can We Globalize?- 2021

Trigeminal neuralgia secondary to onyx embolization of a right occipital arteriovenous malformation- 2021

Pten r130q papillary tumor of the pineal region (Ptpr) with chromosome 10 loss successfully treated with everolimus: A case report- 2021

CSF leak post-anterior clinoidectomy: Case report and technical nuances- 2020